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Significant advances in medical research

CUTTING-EDGE TREATMENTS IMPROVE THE LIVES OF CHILDREN

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ResearcherResearch has always been an integral part of the mission of Texas Children’s Hospital. Since 1954, Texas Children’s strong commitment to research has improved the health and welfare of generations of children.

Known for its expertise and breakthrough developments in the treatment of cancer, newborn diseases, cardiac disorders, diabetes, asthma, HIV/AIDS and attention-related disorders, Texas Children’s is home to the Feigin Center for Pediatric Research – a 200,000-square-foot facility housing more than 120 Texas Children’s and Baylor College of Medicine researchers who seek cures for childhood diseases and conditions.

" Advances in the next 10 years will dwarf anything that we have seen previously."
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Dr. Ralph D. Feigin
Physician-in-Chief
Texas Children's Hospital

 The General Clinical Research Center (GCRC) at Texas Children’s Hospital and Baylor College of Medicine provides a clinical research infrastructure for medical scientists to conduct patient-oriented research.

Many medical advances pioneered at the Feigin Center and the GCRC become cutting-edge treatments for Texas Children’s patients, moving science from the bench to the bedside and resulting in better lives for children.

Texas Children’s was the first hospital to use non-compatible bone marrow transplants to cure severe immunodeficiency disease in children, and the first capable of diagnosing cystic fibrosis prenatally and identifying carriers of the CF gene.

Researchers at Texas Children’s are currently studying subjects such as:

  • Medications to improve the quality of life for children with HIV/AIDS and other chronic illnesses

  • Diganostic methods based on DNA analysis for cystic fibrosis, muscular dystrophy and other genetic disorders

  • Stomach emptying in premature infants

  • Development of treatments gene therapy

  • Better regimes for, and the genetic causes of, pediatric cancer

 

 

Advances in research

Baylor/Texas Children’s physician-investigators have been:

Participants in the first study to demonstrate ways to prevent transmission of HIV from an infected mother to her baby, resulting in thousands of infant lives saved.

Among the first to document the efficacy of surfactant therapy in neonates, resulting in a decline by half in mortality for premature infants.

Credited with the development of the Mullins sheath for left heart catheterization, now the standard equipment used today.

Integral in the isolation of genes responsible for various forms of spinocerebellar ataxia as well as Rett syndrome.

Credited with the development of many of today’s human milk fortifiers used nationally and internationally.

Key to the understanding of group B streptococcal infection – the leading cause of infection death in newborn infants.

Critical to the ultimate approval of many antibiotics and to the approval of many forms of therapy for childhood cancer.

Identifiers of numerous genes and their function, permitting the detection of many inherent diseases in utero or early in life.

Successful in furthering understanding of the molecular basis for seizure disorders of various types.

 
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