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The incidence of babies under 1500 grams with chronic lung disease requiring oxygen at Texas Children’s is 12 percent, compared to a 20 percent national average.
 

   
 

One of the most common ailments of premature babies is respiratory distress syndrome (RDS), caused by under-developed lungs.

Nearly 90 percent of babies who develop RDS now survive, thanks to the use of surfactant, a drug that Texas Children's helped pioneer.

   

RESPIRATORY CARE
Utilizing the latest advances

Respiratory problems are extremely common in premature newborns, affecting 40 to 50 percent of babies born before 32 weeks. One of the most common ailments is respiratory distress syndrome (RDS), caused by underdeveloped lungs. Nearly 90 percent of babies who develop RDS now survive, thanks to the use of surfactant, a treatment Texas Children’s helped pioneer.

Ventilators
Standard and specialized ventilators are used in the NICU. While some newborns are able to breathe well on their own, others may need assistance and require special mixtures of air and oxygen. When breathing assistance is necessary, the baby’s breathing can be measured and the optimal breathing pattern automatically regulated by ventilators.

Surfactant
A major cause of death for premature infants is respiratory failure. Hyaline membrane disease – a result of deficiency of a lung substance called surfactant – is frequently responsible. The lungs of very young preemies often lack the elasticity that surfactant naturally provides. The Texas Children’s Newborn Center has played a major role in the testing of artificial surfactant that is now available commercially and is administered frequently to premature infants to save their tiny lungs.

ECMO
Extracorporeal membrane oxygenation (ECMO) is a form of therapy that supports a baby’s heart and lungs for a few days, providing valuable time for those organs to heal and grow. ECMO technology is similar to the heart/lung bypass techniques used in cardiovascular surgery.

ECMO may be used as therapy for infants who are in critical condition with severe respiratory infections, underdeveloped or malformed lungs, or birth defects.

While it is not a cure for lung disease, ECMO is the stepping stone to survival for many premature infants and has saved the lives of a number of critically ill infants at Texas Children’s.

Nitric oxide (NO) therapy
Nitric oxide (NO) treatment blends nitric oxide gas with the oxygen/air mixture in ventilators to improve blood flow to the lungs. This improves oxygen levels in the baby’s blood, resulting in increased survival rates among newborns treated with NO therapy.

Texas Children’s was the first U.S. hospital to participate in multi-center trials for this highly successful therapy, which sometimes spares the need for more invasive and expensive procedures.

 

 
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