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ADDRESS:
Texas Children’s Hospital
Clinical Care Center, Suite 650
6621 Fannin, CC650.00
Houston, Texas 77030-2399
Phone:
832-822-3135
Fax: 832-825-3141
dcass@bcm.edu
EDUCATION:
1982-1986 Stanford University, Stanford, California
AB, Human Biology, 1986
1986-1991 UCLA School of Medicine, Los Angeles, California
MD, 1991
SPECIALTY: Fetal Surgery, Neonatal, Pediatric Surgery
POSTGRADUATE TRAINING AND
FELLOWSHIP APPOINTMENTS:
1988-1989 Pathology Medical Student Fellow, University Hospitals,
Case Western Reserve University School of Medicine,
Cleveland, Ohio
1991-1994 Intern and Resident in General Surgery,
University of California, San Francisco,
San Francisco, California
1994-1995 Postdoctoral Research Fellow, Fetal Treatment Center,
University of California, San Francisco
1995-1997 Postdoctoral Research Fellow, Center for Fetal Diagnosis
and Treatment and the Children’s Institute for Surgical Science, The
Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
1997-1998 Senior Resident in General Surgery,
University of California, San Francisco
1998-1999 Chief Resident in General Surgery,
University of California, San Francisco
1999-2000 Assistant Chief Resident in Pediatric Surgery,
Michael E. DeBakey Department of Surgery
Baylor College of Medicine, and the Texas Children’s Hospital,
Houston Texas
2000-2001 Chief Resident in Pediatric Surgery,
Michael E. DeBakey Department of Surgery
Baylor College of Medicine, and the Texas Children’s Hospital
FACULTY APPOINTMENTS:
1994-1995 Clinical Instructor in Surgery (in-training)
University of California, San Francisco
1995-1997 Clinical Instructor in Surgery (in-training)
The Children’s Hospital of Philadelphia
2001-present Assistant Professor, Michael E. DeBakey Department of
Surgery,
Baylor College of Medicine
2001-present Assistant Professor, Department of Pediatrics,
Section of Leukocyte Biology, Baylor College of Medicine
2003-present Co-Director, Texas Children's Fetal Center, Texas
Children’s Hospital, St. Luke’s Episcopal Hospital and Baylor
College of Medicine
HOSPITAL APPOINTMENTS:
2001 Active staff, Texas Children’s Hospital, Houston, TX
2001 Active staff, Clear Lake Regional Medical Center,
Houston, TX
2001 Active staff, Ben Taub General Hospital, Houston, TX
2002 Active staff, St. Luke’s Episcopal Hospital, Houston, TX
2002 Provisional active staff, Women’s Hospital of Texas, Houston,
TX
2003 Provisional active staff, St. Luke’s Community Medical
Center-The Woodlands, Woodlands, TX
2004 Provisional active staff, Darnall Army Community Hospital, Fort
Hood, TX
BOARD CERTIFICATION:
American Board of Surgery, 2000 (certificate #45464)
American Board of Surgery,
Special Qualification in Pediatric Surgery, 2002 (certificate #869)
LICENSURE:
Diplomate, National Board of Medical Examiners, 1992
California State Medical License, 1993 - 2003
Texas State Medical License, #L2175, 2001- present
Pennsylvania State Medical License,1995-1997
ADVANCED TRAINING:
Clinical
Advanced Trauma Life Support, Provider
Basic Laparoscopic Surgery Course, 1994
University of California, San Francisco
Advanced Laparoscopic Surgery Course, 1997 and 1999
University of California, San Francisco
Workshop in Surgical Ultrasound, 1998
University of California, San Francisco
Advanced Pediatric Laparoscopic Surgery Course, 1998
University of California, San Francisco
Elective in Pediatric Endosurgery, January 3-31, 2000
Steven Rothenberg, M.D.
Presbyterian/St. Luke’s Hospital
Denver, Colorado
Workshop on the Surgical Treatment of Anorectal Malformations, 2000
Alberto Pena, M.D., Long Island Jewish Medical Center
New Hyde Park, New York
Research
Participant, Gordon Conference on Wound Repair,
Colby Sawyer College, New Hampshire, July 3-8, 1995
“Advanced Immunocytochemistry and in situ Hybridization,” Cold
Spring Harbor Laboratories, October 11-25, 1996
Young Surgical Investigators Conference, American College of
Surgeons, March 8-10, 2002
New England Biolabs Molecular Biology Summer Workshop, Smith
College, Northamptom, MA, June 27 – July 10, 2004
HONORS AND AWARDS:
Valedictorian, Agoura High School, Agoura Hills, California, 1982
Los Angeles County Medical Association Scholarship, 1982
Varsity Letterman, Stanford University Baseball Team, 1982-1986
Borun and Church Scholarships, UCLA School of Medicine, 1986-1991
Alpha Omega Alpha, UCLA School of Medicine, 1990
Juvenile Diabetes Foundation Postdoctoral Fellowship Award, 1995
Best paper, American College of Surgeons, South Texas Chapter, 2000
Vandenberge-Storz Award for best paper by a young investigator,
International Fetal Medicine and Surgery Society, 2001
Lyndon Baines Johnson Research Award, Texas Affiliate, American
Heart Association, 2003
Molecular Surgeon Research Achievement Award, Michael E. DeBakey
Department of Surgery, Baylor College of Medicine, 2003
MEMBERSHIPS IN PROFESSIONAL AND SCIENTIFIC SOCIETIES:
International Societies:
Member, International Fetal Medicine and Surgery Society
Juvenile Diabetes Foundation International
Member, International Pediatric Endosurgery Group
National Societies:
Fellow, American College of Surgeons
Member, Association for Academic Surgery
Fellow, Surgical Section, American Academy of Pediatrics
Member, American Pediatric Surgical Association
Member, American College of Surgeons, South Texas Chapter
Member, Houston Surgical Society
Member, Harris County Medical Society
Member, American Medical Association
Member, Wound Healing Society
Member, Howard C. Nafzigger Surgical Society
American Association for the Advancement of Science
Society for Surgery of the Alimentary Tract
COMMITTEES:
1987-1991 Admissions Committee, UCLA School of Medicine
1988-1989 National Task Force on Universal Health Insurance,
American Medical Student Association
1994-1995 Residency Selection Committee, UCSF Department of Surgery
2003- present Bioethics Committee, Texas Children’s Hospital.
2004- present Peer Review Committee, Texas Children’s Hospital
2004- present Trauma Committee, Texas Children’s Hospital
2005- present Utilization Review Committee, Texas Children’s
Hospital
2005- present Credentialing Committee, Baylor Med Car, Baylor
College of Medicine
RESEARCH SUPPORT:
ONGOING RESEARCH SUPPORT
Beginning Grant-in-Aid 7/1/03-6/30/05 40%
American Heart Association, Texas Affiliate $124,000
“Investigation into Mechanisms of Regenerative Healing in the Fetal
Artery Wall”
Role: PI
Recipient, Lyndon Baines Johnson Research Award for grant
application with most meritorious rating
COMPLETED
R01 HD 25505 Adzick (PI) 3/1/93-2/28/97 40% NIH/NICHD $1,447,051
“Fetal Wound Healing: The Role of the Extracellular Matrix”
Role: Co-Investigator
Postdoctoral Fellowship Award 7/1/95 - 6/30/97 60%
Juvenile Diabetes Foundation International $65,000
“The Role of Cell Adhesion Molecules in Fetal Wound Repair”
Role: PI
Pacific Vascular Research Foundation 7/1/96 - 6/30/97 40%
Research Grant $46,362
“The Fetal Response to Vascular Injury”
Role: PI
TEACHING
Clinical Fellows Supervised
Michael Helmrath, M.D., 2001-2002
Richard Glick, M.D., 2001-2003
Saad Al-Mulhim, M.D., 2001-2003
Jateen Patel, M.D., 2001-2003
Mary Barnes, M.D., 2002-2004
Stephen Muehlstedt, M.D., 2003-present
Naomi Golonka, M.D., 2003-present
Doug Miniati, M.D., 2004-present
Monthly Lecturer to Pediatric Residents (Topics include:
Hirschprung’s Disease, Pediatric Lung Lesions, Abdominal Pain, Fetal
Surgery, Pediatric Trauma, Chest Trauma in Children, Newborn
Surgical Emergencies, Biliary Tract Disorders in Children, Surgical
Pancreatic Disorders in Children)
Medical Student Supervisor and Lecturer during Core Surgical
Rotation, 2001- present
MILITARY
MAJOR, Medical Corps, United States Army Reserves
Service during Operation Noble Eagle, 6/03-9/03
PUBLICATIONS:
Original Papers:
1. Gauderer MW, Cass DL: Meconium per vaginam secondary to ileal
atresia and meconium peritonitis. Pediatr Surg Int 7:64-66, 1992
2. Yamaguchi T, Mullen Y, Watanabe Y, Nomura D, Cass D, Brunicardi
C: Isolation and function of islets from young adult pig pancreas.
Trans Proc 24:1010-1012, 1992
3. Huang XZ, Wu JF, Cass D, Erle D, Corry D, Young SG, Farese RV,
Sheppard D. Inactivation of the integrin 6 subunit gene reveals a
role of epithelial integrins in regulating inflammation in the lungs
and skin. J Cell Biol 133:921-928, 1996
4. Cass DL, Adzick NS: Fetal wound repair renaissance. Oral
Maxillofacial Surg Clin 8:535-546, 1996
5. Cass DL, Bullard KM, Sylvester KG, Yang EY, Sheppard D, Herlyn M,
Adzick NS: Epithelial integrin expression is rapidly upregulated in
human fetal wound repair. Surg Forum 47:765-767, 1996
6. Bullard KM, Cass DL, Adzick NS, Banda MJ: TGF-1 decreases
interstitial collagenase in healing human fetal skin. Surg Forum
47:762-765, 1996
7. Cass DL, Bullard KM, Sylvester KG, Yang EY, Longaker MT, Adzick
NS. Wound size and gestational age modulate scar formation in fetal
wound repair. J Pediatr Surg 32:411-415, 1997
8. Cass DL, Meuli M, Adzick NS: Scar wars: Implications of fetal
wound healing for the pediatric burn patient. Pediatr Surg Int
12:484-489, 1997
9. Cass DL, Crombleholme TM, Howell LJ, Stafford PG, Adzick NS:
Cystic lung lesions with systemic arterial blood supply - A hybrid
of congenital cystic adenomatoid malformation and bronchopulmonary
sequestration. J Pediatr Surg 32:986-990, 1997
10. Cass DL, Sylvester KG, Yang EY, Crombleholme TM, Adzick NS:
Myofibroblast association with scar formation and their absence in
scarless fetal wound repair. J Pediatr Surg 32:1017-1021, 1997
11. Cass DL, Yang EY, Liechty KW, Quinn TM, Crombleholme TM, Flake
AW, Adzick NS: Increased cell proliferation and decreased apoptosis
in congenital cystic adenomatoid malformation: Insights into
pathogenesis. Surg Forum 48:659-661, 1997
12. Yang EY, Cass DL, Sylvester KG, Flake AW, Wilson JM, Adzick NS:
Liver-directed fetal gene therapy using recombinant adenoviral
vectors: Successful readministration in mid-gestation sheep fetuses.
Surg Forum 48:464-467, 1997
13. Bullard KM, Cass DL, Adzick NS, Banda MJ: TGF1 decreases
interstitial collagenase in healing human fetal skin. J Pediatr Surg
32:1023-1027, 1997
14. Sylvester KG, Yang EY, Cass DL, Crombleholme TM, Adzick NS:
Fetoscopic gene therapy of congenital lung disease. J Pediatr Surg
32:964-969, 1997
15. Stelnicki EJ, Bullard KM, Harrison MR, Cass DL, Adzick NS: A new
in vivo model for the study of fetal wound healing. Ann Plast Surg
39:374-380, 1997
16. Liechty KW, Crombleholme TM, Sylvester KG, Lovvorn HN, Kitano YL,
Cass DL, Adzick NS: Differential expression of IL-6 by fetal
fibroblasts. Surg Forum 48:707-709, 1997
17. Kung SH, Hagstrom JN, Cass D, Tai SJ, Lin HF, Stafford DW, High
KA: Human Factor IX corrects the bleeding diathesis of mice with
Hemophilia B. Blood 91:784-790, 1998
18. Cass DL, Bullard KM, Sylvester KG, Yang EY, Sheppard D, Herlyn
M, Adzick NS: Epidermal integrin expression is upregulated rapidly
in human fetal wound repair. J Pediatr Surg 33:312-316, 1998
19. Cass DL, Quinn TM, Yang EY, Liechty KW, Crombleholme TM, Flake
AW, Adzick NS: Increased cell proliferation and decreased apoptosis
characterizes congenital cystic adenomatoid malformation of the
lung. J Pediatr Surg 33:1043-1047, 1998
20. Lovvorn HN, Cass DL, Sylvester KG, Crombleholme TM, Adzick NS,
Savani RC: Hyaluronan receptor expression is increased by fetal
fibroblasts in excisional wounds and correlates with scarring. J
Pediatr Surg 33:1062-1070, 1998
21. Stelnicki EJ, Arbeit J, Cass DL, Saner C, Harrison M, Largman C:
Modulation of the human homeobox genes PRX-2 and HoxB13 in scarless
fetal wounds. J Invest Dermat 111:57-63, 1998
22. Liechty KW, Crombleholme TM, Cass DL, Martin B, Adzick NS:
Diminished Interleukin-8 (IL-8) production in the fetal wound
healing response. J Surg Res 77:80-84, 1998
23. Yang EY, Cass DL, Sylvester KG, Flake AW, Wilson JM, Adzick NS:
BAPS Prize-1997. Fetal gene therapy: Efficacy, toxicity, and
immunologic effects of early gestation recombinant adenovirus. J
Pediatr Surg 34:235-241, 1999
24. Liechty KW, Quinn TM, Cass DL, Crombleholme TM, Flake AW, Adzick
NS: Elevated PDGF-B in congenital cystic adenomatoid malformations (CCAMs)
requiring fetal resection. J Pediatr Surg 34:805-810, 1999
25. Cass DL, Lovvorn HN, Yang EY, Sylvester KG, Adzick NS:
Regenerative capabilities of the fetal vascular wall. Surg Forum
50:468-469, 1999
26. Golshani SD, Lee C, Cass D, Thomas A, Mandpe A: Microvascular
“supercharged” cervical colon: Minimizing ischemia in esophageal
reconstruction. Ann Plast Surg 43:533-538, 1999
27. Lovvorn HN, Savani RC, Ruchelli E, Cass DL, Adzick NS: Serum
hyaluronan and its association with unfavorable histology and
aggressiveness of heterotransplanted Wilms’ tumor. J Pediatr Surg
35:1070-1078, 2000
28. Cass DL, Brandt ML, Patel DL, Nuchtern JG, Minifee PK, Wesson
DE: Peritoneal drainage as definitive treatment for neonates with
isolated intestinal perforation. J Pediatr Surg 35:1531-1536, 2000
29. Cass DL, Hawkins E, Brandt ML, Chintagumpala M, Bloss RS,
Milewicz AL, Minifee PK, Wesson DE, Nuchtern JG: Surgery for ovarian
masses in infants, children and adolescents: 102 consecutive
patients over 15 years. J Pediatr Surg 36:693-699, 2001
30. Cass DL, Wesson DE: Advances in fetal and neonatal surgery for
gastrointestinal anomalies and disease. Clin Perinat 29:1-22, 2002
31. Cass DL: Fetal surgery: applications to increase survival rates.
Neonatal News.Net 3: 1-2, 2002
32. Szigeti K, Wong LC, Perng CL, Saifi GM, Eldin K, Adesina AM,
Cass DL, Hirano M, Lupski JR, Scaglia F: MNGIE with lack of skeletal
muscle involvement and a novel TP slice-site mutation. J Med
Genetics 41:125-129, 2004
33. Glick RD, Hicks MJ, Nuchtern JG, Wesson DE, Olutoye OO, Cass DL:
Renal tumors in infants less than 6 months of age. J Pediatr Surg
39:522-525, 2004
34. Kenton AB, O’Donovan D, Cass DL, Helmrath MA, Washburn K, Weihe
EK, Brandt ML: Severe thrombocytopenia predicts outcome in neonates
with necrotizing enterocolitis. J Perinatol 25:14-20, 2005
35. Kenton AB, Hegemier S, Smith EO, O’Donovan DJ, Brandt ML, Cass
DL, Helmrath MA, Washburn K, Weihe EK, Fernandes CJ: Platelet
transfusions in infants with necrotizing enterocolitis do not lower
mortality but may increase morbidity. J Perinatol 25:173-177, 2005
36. Barnes MJ, Kollenberg SJ, Brandt ML, Wesson DE, Nuchtern JG,
Minifee PK, Cass DL. Surgery for peptic ulcer disease in children in
the post-H2 blocker era. J Pediatr Surg (in press)
37. Cass DL: Ovarian torsion. Semin Pediatr Surg (in press)
38. Cass DL: Fetal surgery for congenital diaphragmatic hernia:
North American Experience. Semin Perinatol (in press)
39. Miniati DN, Chintagumpala M, Dishop M, Langston C, Olutoye OO,
Nuchtern JG, Cass DL. Prenatal diagnosis and outcome of children
with pleuropulmonary blastoma. J Pediatr Surg (submitted)
40. Ambardar S, Cass DL, Barnes MJ, Helmrath MA, Pinsky JR, Brandt
ML: Pilonidal disease in adolescents. (submitted)
41. Olutoye OO, Zhu X, Cass DL, Smith CW: Impaired neutrophil
recruitment by fetal endothelial cells: Implications in scarless
fetal wound healing. (submitted)
Chapters:
1. Cass DL, Adzick NS: Congenital cystic adenomatoid malformation.
In: Ultrasound and Fetal Therapy, Rodeck C, Evans M (eds.),
Parthenon Press, New York, NY, 2000, pp. 49-60
2. Cass DL, Adzick NS: Fetal wound healing implications. In:
Pediatric Oculoplastic Surgery, Katowitz JA (ed), Springer-Verlag,
New York, NY, 2000, pp. 31-42
3. Cass DL, Nuchtern J: Vascular access. In: Pediatric Dialysis,
Warady BA, Alexander SR, Fine RN, Schaefer F (eds), Kluwer Academic
Publishers, Great Britain, 2004, pp. 65-82
4. Cass DL: Fetal Surgery. In: Surgery: Scientific Principles and
Practice, 4th ed. Mulholland M, Lillemoe K, Doherty GM, Maeir A,
Upchurch (eds), Lippincott, Philadelphia, 2005
Book Reviews:
1. Cass DL, Adzick NS. Book Review: Rob and Smith’s Operative
Surgery Series: Pediatric Surgery, 5th ed., Ann Surg
223:441-442,1996
ABSTRACTS:
1. Stelnicki EJ, Holmes D, Klein P, Harrison MR, Bullard KM, Cass
DL, Largman C: The expression of two new homeobox genes FDX-1 and
SDX-1, which are selectively expressed in fetal fibroblasts, is
upregulated during fetal wound healing. Plastic Surgery Education
Foundation, St. Louis, Missouri, June 1, 1996
2. Cass DL, Bullard KM, Sylvester KG, Yang EY, Longaker MT, Adzick
NS: Wound size and gestational age modulate scar formation in fetal
wound repair. XLIII Annual International Congress, British
Association of Pediatric Surgery, St. Helier, Jersey, Channel
Islands, UK, July 16-19, 1996
3. Cass DL, Bullard KM, Sylvester KG, Yang EY, Sheppard D, Herlyn M,
Adzick NS: Epithelial integrin expression is rapidly upregulated in
human fetal wound repair. 82nd Annual Clinical Congress of the
American College of Surgeons, San Francisco, California, October
6-11, 1996
4. Bullard KM, Cass DL, Adzick NS, Banda MJ: TGF-1 decreases
interstitial collagenase in healing human fetal skin. 82nd Annual
Clinical Congress, American College of Surgeons, San Francisco,
California, October 6-11, 1996
5. Cass DL, Bullard KM, Sylvester KG, Yang EY, Adzick NS: Integrin
expression is upregulated rapidly in human fetal repair. 17th Annual
Pediatric Surgical Resident’s Conference, St. Christopher’s Hospital
for Children, Philadelphia, Pennsylvania, October 18-20, 1996
6. Bullard KM, Cass DL, Adzick NS, Banda MJ: TGF-1 decreases
interstitial collagenase in healing human fetal skin. 17th Annual
Pediatric Surgical Resident’s Conference, St. Christopher’s Hospital
for Children, Philadelphia, Pennsylvania, October 18-20, 1996
7. Cass DL, Sylvester KG, Yang EY, Crombleholme TM, Adzick NS:
Myofibroblast association with scar formation and their absence in
scarless fetal wound repair. 48th Annual Meeting, Surgical Section,
American Academy of Pediatrics, Boston, Massachusetts, October
26-30, 1996
8. Cass DL, Crombleholme TM, Howell LJ, Stafford PG, Adzick NS:
Cystic lung lesions with systemic arterial blood supply - A hybrid
of congenital cystic adenomatoid malformation and bronchopulmonary
sequestration. 48th Annual Meeting, Surgical Section, American
Academy of Pediatrics, Boston, Massachusetts, October 26-30, 1996
9. Bullard KM, Cass DL, Adzick NS, Banda MJ: TGF-1 decreases
interstitial collagenase in healing human fetal skin. 48th Annual
Meeting, Surgical Section, Academy of Pediatrics, Boston,
Massachusetts, October 26-30, 1996
10. Sylvester KG, Yang EY, Cass DL, Crombleholme TM, Adzick NS:
Fetoscopic gene therapy of congenital lung disease. 48th Annual
Meeting, Surgical Section, Academy of Pediatrics, Boston,
Massachusetts, October 26-30, 1996
11. Yang EY, Cass DL, Sylvester KG, Flake AW, Wilson JM, Adzick NS:
Immunologic anergy to early gestational administration of
recombinant adenovirus. Poster presentation, Keystone Symposia,
Keystone, Colorado, April, 1997
12. Cass DL, Bullard KM, Sylvester KG, Yang EY, Sheppard D, Herlyn
M, Adzick NS: Epidermal integrin expression is upregulated rapidly
in human fetal wound repair. 28th Annual Meeting, American Pediatric
Surgical Association, Naples, Florida, May 17-20, 1997
13. Yang EY, Cass DL, Sylvester KG, Flake AW, Wilson JM, Adzick NS:
Efficacy and toxicity of adenoviral gene therapy vectors in fetal
sheep lung. Poster presentation, 28th Annual Meeting, American
Pediatric Surgical Association, Naples, Florida, May 17-20, 1997
14. Cass DL, Crombleholme TM, Howell LJ, Stafford PG, Adzick NS:
Cystic lung lesions with systemic arterial blood supply - A hybrid
of congenital cystic adenomatoid malformation and bronchopulmonary
sequestration. 16th International Fetal Medicine and Surgery
Society, Anchorage, Alaska, June 1-5, 1997
15. Cass DL, Bullard KM, Sylvester KG, Yang EY, Sheppard D, Herlyn
M, Adzick NS: Early upregulation of keratinocyte integrins and rapid
reepithelialization in human fetal wound repair. 16th International
Fetal Medicine and Surgery Society, Anchorage, Alaska, June 1-5,
1997
16. Cass DL, Quinn TM, Yang EY, Liechty KW, Crombleholme TM, Flake
AW, Adzick NS: Increased cell proliferation and decreased apoptosis
in congenital cystic adenomatoid malformation: Insights into
pathogenesis. 83rd Annual Clinical Congress of the American College
of Surgeons, Chicago, Illinois, October 12-17, 1997
17. Yang EY, Cass DL, Sylvester KG, Flake AW, Wilson JM, Adzick NS:
Liver-directed fetal gene therapy using recombinant adenoviral
vectors: Successful readministration in mid-gestation sheep fetuses.
83rd Annual Clinical Congress, American College of Surgeons,
Chicago, Illinois, October 12-17, 1997
18. Liechty KW, Crombleholme TM, Sylvester KG, Lovvorn HN, Kitano YL,
Cass DL, Adzick NS: Differential expression of IL-6 by fetal
fibroblasts. 83rd Annual Clinical Congress, American College of
Surgeons, Chicago, Illinois, October 12-17, 1997
19. Cass DL, Quinn TM, Yang EY, Liechty KW, Crombleholme TM, Flake
AW, Adzick NS: Increased cell proliferation and decreased apoptosis
characterizes congenital cystic adenomatoid malformation of the
lung. 49th Annual Meeting, Surgical Section, American Academy of
Pediatrics, New Orleans, LA, November 1-5, 1997
20. Liechty KW, Crombleholme TM, Sylvester KG, Lovvorn HN, Kitano Y,
Cass DL, Adzick NS: Differential IL-6 production by fetal vs. adult
fibroblasts. Poster presentation, 49th Annual Meeting, Surgical
Section, American Academy of Pediatrics, New Orleans, Louisiana,
November 1-5, 1997
21. Lovvorn HN, Cass DL, Sylvester KG, Crombleholme TM, Adzick NS,
Savani RC: Hyaluronan receptor expression is increased by fetal
fibroblasts in excisional wounds and correlates with scarring. 49th
Annual Meeting, Surgical Section, American Academy of Pediatrics,
New Orleans, Louisiana, November 1-5, 1997
22. Liechty KW, Crombleholme TM, Sylvester KG, Lovvorn HN, Kitano YL,
Cass DL, Adzick NS: Diminished IL-6 production by fetal vs. adult
fibroblasts in response to PDGF stimulation. The Association for
Academic Surgery, Dallas, Texas,
November 8, 1997
23. Yang EY, Cass DL, Sylvester KG, Flake AW, Wilson JM, Adzick NS:
BAPS Prize-1997. Fetal gene therapy: Efficacy, toxicity, and
immunologic effects of early gestation recombinant adenovirus. 45th
Annual International Congress of the British Association of
Pediatric Surgeons, Bristol, England, July 21-24, 1998
24. Liechty KW, Quinn TM, Cass DL, Crombleholme TM, Flake AW, Adzick
NS: Elevated PDGF-B in congenital cystic adenomatoid malformations (CCAMs)
requiring fetal resection. 50th Annual Meeting, Surgical Section,
American Academy of Pediatrics, San Francisco, California, October
19, 1998
25. Crombleholme TM, Liechty KW, Cass DL, Johnson MP, Flake AW,
Howell LJ, Adzick NS: Natural history of fetal cystic adenomatoid
malformation of the lung: Biologic behavior in hydropic CCAMs.
International Fetal Medicine and Surgery Society, Carlisle, UK, May
21, 1999
26. Cass DL, Lovvorn HN, Yang EY, Sylvester KG, Adzick NS:
Regenerative capabilities of the fetal vascular wall. 85th Annual
Clinical Congress of the American College of Surgeons, San
Francisco, California, October 11-15, 1999
27. Cass DL, Brandt ML, Patel DL, Nuchtern JG, Minifee PK, Wesson
DE: Peritoneal drainage as definitive treatment for isolated
intestinal perforation in neonates less than 1000 grams. Annual
Meeting, American College of Surgeons, South Texas Chapter, San
Antonio, Texas, February 18-19, 2000
28. Cass DL, Brandt ML, Patel DL, Nuchtern JG, Minifee PK, Wesson
DE: Drainage alone in newborn gastrointestinal perforation. 33rd
Annual Meeting, Pacific Association of Pediatric Surgeons, Las
Vegas, Nevada, May 15-19, 2000
29. Cass DL, Hawkins E, Brandt ML, Chintagumpala M, Bloss RS,
Milewicz AL, Minifee PK, Wesson DE, Nuchtern JG: Surgery for ovarian
masses in infants, children and adolescents: 102 consecutive
patients over 15 years. 33rd Annual Meeting, Canadian Association of
Pediatric Surgeons, Montebello (Quebec), Canada, September 15-18,
2000
30. Cass DL, Hawkins E, Brandt ML, Chintagumpala M, Bloss RS,
Milewicz AL, Minifee PK, Wesson DE, Nuchtern JG: Surgery for ovarian
masses in infants, children and adolescents: 102 consecutive
patients over 15 years. Annual Meeting, American College of
Surgeons, South Texas Chapter, San Antonio, Texas, March 2-3, 2001
31. Cass DL, Lovvorn HN, Yang EY, Sylvester KG, Adzick NS:
Regenerative capabilities of the injured fetal artery. 20th
International Fetal Medicine and Surgery Society, Kruger, South
Africa, October 1-5, 2001.
32. Cass DL, Olutoye OO, Adam K, Coleman B, Hubbard A, Adzick NS:
Prenatal diagnosis and management of congenital lobar emphysema.
21st International Fetal Medicine and Surgery Society, Quebec,
Canada, September 1-4, 2002
33. Cass DL, Olutoye OO, Adam K, Brandt ML: Successful use of
‘minimally invasive repair’ of gastroschisis. 20th International
Fetal Medicine and Surgery Society, Kruger, South Africa, October
1-5, 2001
34. Ambardar S, Cass DL, Barnes MJ, Helmrath MA, Pinsky JR, Brandt
ML: Pilonidal disease in adolescents. Annual Meeting, American
College of Surgeons, South Texas Chapter, Houston, Texas, March 7-8,
2003
35. Olotoye OO, Zhu X, Cass DL, Smith CW: Age-dependent variations
in endothelial cell function. 22nd Annual Meeting, International
Fetal Medicine and Surgery Society, Zermatt, Switzerland, April
27-30, 2003
36. Glick RD, Hicks MJ, Nuchtern JG, Wesson DE, Olutoye OO, Cass DL:
Renal tumors in infants less than 6 months of age. Poster
Presentation, 34th Annual Meeting of the American Pediatric Surgical
Association, Fort Lauderdale, FL, May 25-28, 2003
37. Ambardar S, Cass DL, Barnes MJ, Helmrath MA, Pinsky JR, Brandt
ML: Pilonidal disease in adolescents. 34th Annual Meeting of the
American Pediatric Surgical Association, Fort Lauderdale, FL, May
25-28, 2003
38. Cass DL, Lovvorn HN, Yang EY, Sylvester KG, Adzick NS:
Regenerative capabilities of the fetal vascular wall. 65th Annual
Meeting of the Society of University Surgeons, St. Louis, MO,
February 13, 2004
39. Cass DL, Cassady CI, Wilkins I, O’Day MP, Coverler L, Adam K,
Adzick NS, Olutoye OO. Prenatal diagnosis and outcome of fetuses
with giant neck masses. 23rd International Fetal Medicine and
Surgery Society, Charleston, SC, March 14-17, 2004
40. Barnes MJ, Kollenberg SJ, Brandt ML, Wesson DE, Nuchtern JG,
Minifee PK, Cass DL. Surgery for peptic ulcer disease in children in
the post-H2 blocker era. Annual Meeting, American College of
Surgeons, South Texas Chapter, Houston, Texas, March 31- April 1,
2004
41. Kenton AB, O’Donovan D, Cass DL, Helmrath MA, Washburn K, Weihe
E, Brandt ML: Severe thrombocytopenia predicts outcome in neonates
with necrotizing enterocolitis. Pediatric Academic Societies’ Annual
Meeting, May 1-4, 2004, San Francisco, CA
42. Zhu X, Cass DL, Smith CW, Olutoye OO: Lower expression of P-selectin
may modulate the fetal inflammatory response. 14th Annual Meeting of
the Wound Healing Society, Atlanta, GA, May 23-26, 2004
43. Cass DL, Cassady C, O’Day M, Coveler L, Olutoye OO. Prenatal
diagnosis and outcome of fetuses with giant neck masses. Michael E.
DeBakey International Surgical Society, XVth Congress, May 15-17,
2004
44. Olutoye OO, Zhu X, Cass DL, Smith CW: Impaired neutrophil
recruitment by fetal endothelial cells: implications in scarless
fetal wound healing. 35th Annual Meeting of the American Pediatric
Surgical Association, May 27-31, 2004
45. Barnes MJ, Kollenberg SJ, Brandt ML, Wesson DE, Nuchtern JG,
Minifee PK, Cass DL. Surgery for peptic ulcer disease in children in
the post-H2 blocker era. Canadian Association of Paediatric
Surgeons, September 30-October 3, 2004, Winnipeg, Manitoba, CANADA
46. Brandt ML, Cass DL. Spontaneous resolution of prenatal ovarian
torsion. Canadian Association of Paediatric Surgeons, September
30-October 3, 2004, Winnipeg, Manitoba, CANADA
47. Cass DL, Cassady CI, O’Day MP, Coveler LA, Adzick NS, Wesson DE,
Olutoye OO: Predictors of airway obstruction and outcome of fetuses
with giant neck masses. American Academy of Pediatrics, October
8-10, 2004, San Francisco, CA
48. Muehlstedt SG, Hicks MJ, Brandt MJ, Washburn KK, Wesson DE,
Nuchtern JG, Cass DL. Incidence of viable ovarian tissue after
resection for ovarian torsion in children. American Academy of
Pediatrics, October 8-10, 2004, San Francisco, CA
49. Cass DL, Cassady CI, O’Day MP, Coveler LA, Wesson DE, Olutoye OO:
Predictors of airway obstruction and outcome of fetuses with giant
neck masses. American College of Surgeons, South Texas Chapter,
Houston, TX, March 11-12, 2005
50. Miniati DN, Chintagumpala M, Langston C, Olutoye OO, Nuchtern JG,
Cass DL. Prenatal diagnosis and outcome of children with
pleuropulmonary blastoma. American College of Surgeons, South Texas
Chapter, Houston, TX, March 11-12, 2005
51. Muehlstedt SG, Hicks MJ, Washburn KK, Brandt MJ, Wesson DE,
Helmrath MA, Nuchtern JG, Cass DL. Management of ovarian torsion in
children: Clinicopathologic Correlation. American College of
Surgeons, South Texas Chapter, Houston, TX, March 11-12, 2005
52. Golonka NR, Kaplan SL, Mason EO, Olutoye OO, Wesson DE, Cass DL,
Nucthern JG. Operative drainage shortens length of stay for children
with staphylococcal skin abscesses. American College of Surgeons,
South Texas Chapter, Houston, TX, March 11-12, 2005
53. Miniati DN, Chintagumpala M, Langston C, Olutoye OO, Nuchtern JG,
Cass DL. Prenatal diagnosis and outcome of children with
pleuropulmonary blastoma. American Pediatric Surgery Association.
May, 2005, Phoenix, AR
INVITED LECTURES:
1. “Scarless fetal wound repair.” Grand Rounds, UCSF Department of
Surgery, San Francisco, California, May 14, 1998
2. “Perineal one stage operative pull-through (POOP) procedure for
Hirschsprung’s Disease.” Grand Rounds, UCSF Department of Surgery,
San Francisco, California, November 11, 1998
3. “Gastroesophageal reflux disease: Current diagnosis and
management.” Grand Rounds, UCSF Department of Surgery, San
Francisco, California, January 21, 1999
4. “Hirschprung’s disease.” Grand Rounds, Department of Surgery, Ben
Taub General Hospital and the Baylor College of Medicine, Houston,
Texas, April 19, 2000
5. “Fetal surgery for congenital malformations.” Grand Rounds,
Department of Surgery, Ben Taub General Hospital and the Baylor
College of Medicine, Houston, Texas, May 31, 2000
6. “Hirschprung’s disease and the newborn,” Grand Rounds, Department
of Pediatrics, Division of Neonatology, Baylor College of Medicine,
Texas Children’s Hospital, Houston, Texas, June 7, 2000
7. “Ovarian masses in children,” Pediatric residents conference,
Texas Children’s Hospital, Houston, Texas, November 8, 2000
8. “Biliary tract disorders in childhood,” Pediatric residents
conference, Texas Children’s Hospital, Houston, Texas, April 11,
2001
9. “CPC: A case of necrotizing enterocolitis and isolated intestinal
perforation,” Grand Rounds, Department of Pediatrics, Baylor College
of Medicine, Texas Children’s Hospital, October 26, 2001
10. “Update on fetal surgery.” 25th Annual Baylor Perinatal
Symposium, Houston, TX, November 2, 2001
11. “Update on fetal surgery,” Grand Rounds, Department of
Pediatrics, Division of Neonatology, Baylor College of Medicine,
Texas Children’s Hospital, Houston, Texas, February 1, 2002
12. “Fetal Surgery,” Houston Area Association of Neonatal Nurses,
Annual Meeting, Houston, Texas, April 4, 2002
13. “Wound repair: An Overview of Adult and Fetal Repair,” Grand
Rounds, Michael E. DeBakey Department of Surgery, Baylor College of
Medicine, April 10, 2002
14. “Surgery on the Fetus,” General Surgery Grand Rounds, St. Luke’s
Episcopal Hospital, December 10, 2002
15. “Fetal Surgery for Congenital Structural Anomalies.” Pediatrics
Grand Rounds, Texas Children’s Hospital and the Baylor College of
Medicine, March 14, 2003
16. “Advances in Fetal Surgery.” Obstetrics and Gynecology Grand
Rounds, Baylor College of Medicine, April 30, 2003
17. “Update on Fetal Surgery.” 27th Annual Baylor Perinatal
Symposium, Houston, TX, October 24, 2003
18. “Choosing a Job: The Academic Perspective.” American Academy of
Pediatrics-- Pediatric Surgery Residents’ Conference, October 8,
2004, San Francisco, CA
19. “Update on Fetal Surgery.” Grand Rounds, Internal Medicine
Service, St. Luke’s Episcopal Hospital, November 15, 2004
PRESENTATIONS (NATIONAL OR INTERNATIONAL MEETINGS):
1. “Wound size and gestational age modulate scar formation in fetal
wound repair.” XLIII Annual International Congress, British
Association of Pediatric Surgery, St. Helier, Jersey, Channel
Islands, UK, July 16-19, 1996
2. “Epithelial integrin expression is rapidly upregulated in human
fetal wound repair.” 82nd Annual Clinical Congress of the American
College of Surgeons, San Francisco, California, October 6-11, 1996
3. “Integrin expression is upregulated rapidly in human fetal
repair.” Seventeenth Annual Pediatric Surgical Resident’s
Conference, St. Christopher’s Hospital for Children, Philadelphia,
Pennsylvania, October 18-20, 1996
4. “Myofibroblast association with scar formation and their absence
in scarless fetal wound repair.” 48th Annual Meeting, Surgical
Section, American Academy of Pediatrics, Boston, Massachusetts,
October 26-30, 1996
5. “Cystic lung lesions with systemic arterial blood supply - A
hybrid of congenital cystic adenomatoid malformation and
bronchopulmonary sequestration.” 48th Annual Meeting, Surgical
Section, American Academy of Pediatrics, Boston, Massachusetts,
October 26-30, 1996
6. “Epidermal integrin expression is upregulated rapidly in human
fetal wound repair.” 28th Annual Meeting, American Pediatric
Surgical Association, Naples, Florida, May 17-20, 1997
7. “Cystic lung lesions with systemic arterial blood supply - A
hybrid of congenital cystic adenomatoid malformation and
bronchopulmonary sequestration.” 16th International Fetal Medicine
and Surgery Society, Anchorage, Alaska, June 1-5, 1997
8. “Early upregulation of keratinocyte integrins and rapid
reepithelialization in human fetal wound repair.” 16th International
Fetal Medicine and Surgery Society, Anchorage, Alaska, June 1-5,
1997
9. “Increased cell proliferation and decreased apoptosis in
congenital cystic adenomatoid malformation: Insights into
pathogenesis.” 83rd Annual Clinical Congress of the American College
of Surgeons, Chicago, Illinois, October 12-17, 1997
10. “Increased cell proliferation and decreased apoptosis
characterizes congenital cystic adenomatoid malformation of the
lung.” 49th Annual Meeting, Surgical Section, American Academy of
Pediatrics, New Orleans, LA, November 1-5, 1997
11. “Increased cell proliferation and decreased apoptosis in
congenital cystic adenomatoid malformation.” 11th Annual Resident
Research Day, University of California, San Francisco; San
Francisco, California, February 27, 1998
12. “Regenerative capabilities of the fetal vascular wall.” 85th
Annual Clinical Congress of the American College of Surgeons, San
Francisco, California, October 11-15, 1999
13. “Peritoneal drainage as definitive treatment for isolated
intestinal perforation in neonates less than 1000 grams.” Annual
Meeting, American College of Surgeons, South Texas Chapter, San
Antonio, Texas, February 18-19, 2000 (Winner, “Best Paper” in
Resident Competition)
14. “Drainage alone in newborn gastrointestinal perforation.” 33rd
Annual Meeting, Pacific Association of Pediatric Surgeons, Las
Vegas, Nevada, May 15-19, 2000
15. “Surgery for ovarian masses in infants, children and
adolescents: 102 consecutive patients over 15 years.” 33rd Annual
Meeting, Canadian Association of Pediatric Surgeons, Montebello
(Quebec), Canada, September 15-18, 2000
16. “Pancreas mass in a 3 year-old boy.” 21st Annual Pediatric
Surgery Resident’s Conference, Chicago, Illinois, October 27, 2000
17. “Surgery for ovarian masses in infants, children and
adolescents: 102 consecutive patients over 15 years.” American
College of Surgeons, South Texas Chapter, San Antonio, TX, March
2-3, 2001
18. “Regenerative capabilities of the injured fetal artery.” 20th
International Fetal Medicine and Surgery Society, Kruger, South
Africa, October 1-5, 2001.
- Winner, Vandenberge-Storz Award for best paper by a young
investigator.
19. “Successful use of ‘minimally invasive repair’ of gastroschisis.”
20th International Fetal Medicine and Surgery Society, Kruger, South
Africa, October 1-5, 2001
20. “Prenatal diagnosis and management of congenital lobar
emphysema.” 21st International Fetal Medicine and Surgery Society,
Quebec, Canada, September 1-4, 2002
21. “Regenerative capabilities of the fetal vascular wall.” 65th
Annual Meeting of the Society of University Surgeons, St. Louis, MO,
February 13, 2004
22. “Prenatal diagnosis and outcome of fetuses with giant neck
masses.” 23rd International Fetal Medicine and Surgery Society,
Charleston, SC, March 14-17, 2004
23. “Prenatal diagnosis and outcome of fetuses with giant neck
masses.” Michael E. DeBakey International Surgical Society, XVth
Congress, May 15-17, 2004
24. “Spontaneous resolution of prenatal ovarian torsion.” Canadian
Association of Pediatric Surgeons, Winnepeg, CANADA, September
30-October 3, 2004
25. “Predictors of airway obstruction and outcome of fetuses with
giant neck masses.” American College of Surgeons, South Texas
Chapter, Houston, TX, March 12, 2005
 
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